Small RNA regulators of social behaviour in eutherian mammals

Title: Small RNA regulators of social behaviour in eutherian mammals
Creator: Cairns, Murray J.
Relation: NHMRC.1121474 http://purl.org/au-research/grants/nhmrc/1121474
Relation: EMBO Reports Vol. 20, Issue 2, no. e47663
Publisher Link: http://dx.doi.org/10.15252/embr.201947663
Publisher: Wiley-Blackwell
Resource Type: journal article
Date: 2019
Description: Small non-coding miRNA appear to be vital in brain development and function by organising complex patterns of gene expression. These molecules are important for the regulation of synaptically localised mRNAs that encode proteins involved in neurotransmission and behaviour. In this issue of EMBO Reports, Lackinger et al demonstrate that a large cluster of miRNAs, that emerged in placental mammals, functions as a repressor of social behaviour. This discovery has significant implications for our understanding of the brain, behaviour and in particular psychiatric syndromes, which have been shown to display alterations of these molecules.
Subject: small RNA regulators; social behaviour; eutherian mammals; brain development
Identifier: http://hdl.handle.net/1959.13/1466845
Identifier: uon:47678
Identifier: ISSN:1469-221X
Language: eng
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